GCH1-Polymorphism and Pain Sensitivity among Women with Provoked Vestibulodynia
نویسندگان
چکیده
منابع مشابه
GCH1-polymorphism and pain sensitivity among women with provoked vestibulodynia
BACKGROUND Provoked vestibulodynia (PVD) is a pain disorder localized in the vestibular mucosa. It is the most common cause of dyspareunia among young women and it is associated with general pain hypersensitivity and other chronic pain conditions. Polymorphism in the guanosine triphosphate cyclohydrolase (GCH1) gene has been found to influence general pain sensitivity and the risk of developing...
متن کاملMucosal versus muscle pain sensitivity in provoked vestibulodynia
BACKGROUND An estimated 8.3%-16% of women experience vulvovaginal discomfort during their lifetime. Frequently these patients report provoked pain on contact or with attempted intercourse, commonly referred to as provoked vestibulodynia (PVD). Despite the burden of this condition, little is known about its potential etiologies including pelvic floor muscular dysfunction and mucosal components. ...
متن کاملAcceptance of vulvovaginal pain in women with provoked vestibulodynia and their partners: associations with pain, psychological, and sexual adjustment.
INTRODUCTION Provoked vestibulodynia (PVD) is a common vulvovaginal pain condition associated with negative psychological and sexual consequences for affected women and their sexual partners. Greater pain acceptance has been found to be associated with better functional and psychological outcomes in individuals with chronic pain, and acceptance-based strategies are being increasingly incorporat...
متن کاملProvoked vestibulodynia: current perspectives
Provoked vestibulodynia (PVD) refers to vulvar pain of at least 3 months duration, localized to the vestibule, provoked by touch and sexual activity and occurring in the absence of a clear identifiable cause. The clinical spectrum ranges from mild with distressing discomfort through to severe and disabling pain. Current understanding is that PVD is one of many chronic pain conditions characteri...
متن کاملFear avoidance and self-efficacy in relation to pain and sexual impairment in women with provoked vestibulodynia.
BACKGROUND Provoked vestibulodynia is believed to be the most frequent cause of vulvodynia in women of childbearing age, with prevalence rates of up to 12% in the general population. Despite this high prevalence and the fact that vestibulodynia impacts negatively on quality of life, in particular sexual functioning, there has been a paucity of sound research to elucidate the condition's etiolog...
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ژورنال
عنوان ژورنال: Molecular Pain
سال: 2012
ISSN: 1744-8069,1744-8069
DOI: 10.1186/1744-8069-8-68